Evaluation of bone healing capacity of xenogenic tooth bone graft material with polydeoxyribonucleotide in bone defect surrounding an implant
이지영, 김영균, 윤필영, 박주철, Ahn Kyo-Jin, 김수연,
소속 상세정보
이지영 ( Lee Ji-Young ) - Seoul National University Bundang Hospital Department of Oral and Maxillofacial Surgery
김영균 ( Kim Young-Kyun ) - Seoul National University Bundang Hospital Department of Oral and Maxillofacial Surgery
윤필영 ( Yun Pil-Young ) - Seoul National University Bundang Hospital Section of Dentistry Department of Oral and Maxillofacial Surgery
박주철 ( Park Ju-Cheol ) - Seoul National University School of Dentistry Oral Histology
( Ahn Kyo-Jin ) - Seoul National University Bundang Hospital Section of Dentistry Department of Oral and Maxillofacial Surgery
김수연 ( Kim Soo-Yeon ) - KOREA INTERNATIONAL
KMID : 0353320140380010009
Abstract
Purpose: The purpose of the study was to evaluate the bone healing capacity of a xenogenous tooth bone graft material with PDRN (polydeoxyribonucleotide) in a bone defect surrounding an implant in a beagle dog. We compared bone healing capacity between a xenogenic bone graft material (BioOss; Geistlich Pharma AG, Wolhausen, Switzerland) and xenogenous tooth bone graft material. Materials and Methods: The immediate implant placement was done on the 2nd and 3rd premolar extracted sites on both maxilla in six beagle dogs. Artificial bone defects (four in each dog) were made with a length of 5 mm and width of 5 mm. Bone grafts were performed as follows: the xenogenous tooth bone graft material only in group 1; xenogenous tooth bone graft material mixed with PDRN in group 2; xenogenous bone graft material only in group 3; and xenogenous bone graft material mixed with PDRN in group 4. Sacrifices were performed 2, 4, 8 weeks after the experiment. Bone volume ratio around the implant was evaluated through micro-computed tomography. Results: Bone volume ratio around the implant threads increased gradually over time. Groups 2 and 4 showed higher bone volume ratios than groups 1 and 3. Conclusion: Within the limitations of the study, we conclude that application of a bone graft material mixed with PDRN might promote the bone healing process.
키워드
Polydeoxyribonucleotides; Tooth; Bone
원문 및 링크아웃 정보
등재저널 정보